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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '059158a8a23b2131396a48c7d78e6834652c1965404d7af959dcb85af54f722c' 
  AND token = 'ak8LhVvMzSiTtG+GRsrfR4YrKHELb8kiedR+sPuzxDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}