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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edc014b08cab2afc901e8a223328b0f01e4ad362d0147f235b9ab7dd012c8ab2' 
  AND token = 'Zr+uQVDqnmN8nRLjF1VLkMzlTKLIBp+uNln7LhKa45A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}