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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e01fe05625ad6681d96924dc9e5577c017cb5fdf44a8097c72bb702a2c040d64' 
  AND token = 'zDAntO6iEg0bCxTMCmQV3M9EqF3Z6dFT0zfblsF4D+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}