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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a22e6bc1ce18eb14bc06f133413afe7735c155a504402e736145e258f9f9a330' 
  AND token = '5NtI7IUv+7JN3yWrPBGXMZJpCDe1wtCR9wpzC+VxKVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}