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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6287e600481cca610e1587a48bd9d8d0ac24f9b9f0e6437236b5f8ae86cc304d' 
  AND token = 'B7S50MkCfHeax2FLgMMaGnT47hAl1k+60jbKxe5/zIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}