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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a508a46fd67b1f40b32d8644d6bd8e693f3dd9ad4a7fffb046ed465f0465873c' 
  AND token = 'c2rdvEID2/FW9yMk2ZG9xpCmWttCkYt2tkew2YjDql0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}