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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e072d83c16e80283c0746945b17b22c57def705fb2fcb8e2042d0b5dcff52726' 
  AND token = 'eO2bH/X/RxjVSXHOsgL8fcjMpSBjlQldqqLgadPKN5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}