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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1e9247ad909ee519a2349f30767ef3765ae656f0c18661144c22d7e62139099' 
  AND token = 'MGI9AFeMX5y4azR7nmDP4+tqpbnowCYQcpHF4QHMAzM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}