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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a8ebd1cfba6edf50a39c7f9449827b0a7495889c707f1d800f5fd48ce718d78' 
  AND token = 'cE6vc/3sk1+2HAY+qRBEYpkXl25MDxf1MbVpodKL5Jo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}