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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ad832684b9f671952afe7e5ace35cb3cc06c05c49e153b0c6b0eeb2d0c5b59a' 
  AND token = 'zv1mtf4GpCHcPFFTvKG3SN4eH2p/5++UrRJmprXa1UQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}