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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a83437e5b2035a0a8f1f663f9d36850928ec53e8d33c1e30abca416d8b67417' 
  AND token = 'KXntCwpJXICeASqleS0bPlmp9oG6/tAJmE8EARuyOCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}