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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00727fa9238283ca40e4478b45b1b273db16889619481da09f19bb91fff8415a' 
  AND token = 'liZfeXg+r68yQWfDfRt+5ehDdray/1T9kq2hYfKv/Wc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}