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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7917364fe64275e52f8224a84ae5e5e126702374524b08b28dd28997531fb619' 
  AND token = 'P//SSpoUEo27pC1ioe+icg33k5XC2MdvqTSwOJMjpK4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}