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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '328410fde4069ca20c32c8978af83ac80593cb6bb08442a16fbbcc1ce3d5d180' 
  AND token = '/a9I3TeUK3ZhUxY5nNZ8khZ7ZCzTaTOpU7IX3Bc7blY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}