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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fa0409d58bdfca38f5360f58a0cc33a3e1903e16287439aa733634278c39801' 
  AND token = 'WI6NPyI9FZq871RNyyW3/ipOXn/3gJjLzNuw/iS5HPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}