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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9def8aabed8c7acee3691c8228ad42c6ab31b1dc4bd30dd035f28c8673f9962' 
  AND token = 'piULvQMa+E7b7CYVjprAEUpcL373StNa2+zDtHSX1AY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}