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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e26ec5c2adef6f87d200ef485470adfc3b1213f6044a583be0f1e7147b58451' 
  AND token = 'xyoDYdzXGppC/QJRjEADxKRnzJv6XBv5feL3GTp1VzU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}