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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c47d3afbe9939d123bd140a51c8b0b590cb784d19b4a84ea582e509b7460e270' 
  AND token = 'K/PI+cq+NzKv0mRr0Vg70lmCgU0eHpO29lUjZuzkGNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}