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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '848b37c1483bc049b83a944434275970b2dc90dba415c58ad172c75b54ce5f8c' 
  AND token = 'cz+d/yImvMWgn+d/TxFXmv40XN+yLn0OTq6RNmidcqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}