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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd3be64a212764f145de4f4734fe109f5bf633cae23b89550c1d7eeb2a4717e2' 
  AND token = 'Ayp2nGWoPJ39g/OOtIf08I+4zvFBxaIkKuP0WkAjB5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}