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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '898d54b318d4d42b54bda7e859809e4738278a9ff01364da4aff8151a7e1c7ef' 
  AND token = 'UhqepjzyinDlFDVV2K7BFpdFHf2y8+AchpjsPxXeo1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}