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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72938ef78f769ed1a3a0e72123ff2fbe6565e78a7f767c5f9933e9047e00f497' 
  AND token = 'Bnyngfu0lUAec7/calJsl5EiOgRh2IC472tWfTk6Md8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}