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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b4797df0f8b24b86785f11163a6db5b5cb09b508662734d1ba1c100ae46e195' 
  AND token = '0jVRoZSITX9dWgSZ0Mnan3L4LElGodCtU4TkNqGJJao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}