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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d835f36d8790ad9f5c5da03e872e44d84d6783129ca547d8566718a6301b99e' 
  AND token = 'rKzNq/Z4NFBWUWV9eQN1IGMo/a0YKn2DgYenKf/tuxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}