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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53f4368c2e921c432ba0fb1a427cab183f461b263074b2cdf4e88a0539c20eb3' 
  AND token = 'LopIoQ9JFO2RnSHujNoBdkmbpd+A5Tp90HQr3+DQ1tY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}