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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdfb578d2efc6425379a9059300b1227004c24a62a78ff5efb4cac81e2826246' 
  AND token = 'J6O1FISNEB3wqjY7Ad9yioTr19BTewRFX+VMWiNwHqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}