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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6dc972789aaad5027344a62b674db2300a5da3cb07aee8df69d61abf8a061d5' 
  AND token = '5OKFqUkKBk3hRdNubDDqPC9M+2L04quKVOQVUEa1+O8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}