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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e5ea326c505dffaa2e5a54d581f54cd0039337897f240899136eab9fa8f09d6' 
  AND token = '1hR0Ut8yEPrfGme7yyWOuQgdXktxFOmFxBCPgJ1FMYQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}