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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5dde5e3ecf0ff5447148e0d371994821f83c540e82d86e84e3165cc7a9de61e5' 
  AND token = 'FfwK5+MXPwiFWOR9Nn+PcSQB2egC1HNnlVEANbhza9w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}