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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8b501e42bce4d28b548f53b3fd7b38bcab450bf97723640171e59f59e8570f4' 
  AND token = 'QZnXLbryL1CuaNz5QcYX1HQnlDFnINNHCcMXWyesd4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}