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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21b04926a439826eab7905eadf30f9c9d9c6c3cc80e0e1d57608aea75c3da20c' 
  AND token = 'o15vdONTbeMCqRLO9e0CHt5IWUxmv73TWQvvcQkfq7s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}