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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e706a3fcd7f544a448dc2885b2661c3f4974e34d0804a5a6ffbb4f5a009d6a7' 
  AND token = 'iytroduz0HZCvSrLCm/13jMTrE/ESNnBLHmMme0xReM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}