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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab263eb8c3b37af41549c4b1aed7f24b302a219cfc36780d5b5568affe383e04' 
  AND token = 'C/jaYO5mpmb2LYix5LC7yThvdX3X31i3kGftH5qZYxY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}