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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f0c7be6536412ba5925f920c67a4710711080f7ee1f4cca8adf2994eb2c2122' 
  AND token = 'O76qhIIbmR6gKA/cfGI1c9Zx+0grhqExL0a4b1Myeow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}