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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '62afa24d73eab8df31d5fc9939b797ae1a309ae6c3c5759d46c90194e26b0545' 
  AND token = 'XsbVr0DnKPVhd5m0RWo9RdCB6b6nPpUVlrnlSjqI92g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}