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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d9f94734694aa1aa14b773a5ff40ae9ba832fb1423a200f218e14ccedc8e470' 
  AND token = 'Yq0J7rG/sFaX/iA3fjJVXTt4iUriDjzK8NiFCnkNqO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}