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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d6ae4ab19bbfe37ff17a6097323834742509b2d1ff5ab15599bcc3e51ee3243' 
  AND token = 'l18HMTwDRZmMkiamu8WuoK6aTJ8/5vdImwjRijOLAIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}