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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c99825ef0b564ac58b16b6b06bdabac530240c6bf9f09f9cc1c3bfca7a48736a' 
  AND token = 'PZb1hbWO75GZ+0iqXD1gI7gKIYSqJEDWo0DLYcYuJwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}