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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '812ad0375849a12a49646a5a7b276db0655521acfdd69574148a2258ff6a07a8' 
  AND token = 'qntpbxshCILsUyfV6V2Aw7hkJ/Qv1TXcqdvkC0rwXks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}