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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a077a7f53070ad64b1b3228fa17cbcbdcdc488f452d9a553530268beb10dbff' 
  AND token = 'qgIn6Kr9tU0K/njiWBoL10kCUdIKqb6SDDgxp4QHG7g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}