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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3f6049e0fbc290bda47b3de74b0960ab64dc3a0850447f22d55316168905010' 
  AND token = 'jEwuyhMPheUSLHmnpPm+wM48oYPyJJ5I8Q7LtxT19+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}