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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff02f69f158a9b4abdc0d8a167dda91dee67c2a46d3f206fc47e763fa881373d' 
  AND token = 'HgUTmfHScQJ1SXvt0pGrb/8d5V0xnkARiH58nFFSI8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}