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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1048648da615b57a741d37dbeebba9f9ee4b5f6e5dbd29ef6f32eff600481d16' 
  AND token = '4maJ+s4lPM7YNqYfpaMUCJ0Kpckw2yEhuXnwLIknRPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}