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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ce0440632c0794a6be7a75dcfe74cc42b704f8624090dd371352a208c87c44e' 
  AND token = 'hlLtp/+UFlx1lJ0o1RZARQ0cX9Eqak9ju6L4gl0fQwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}