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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72339df5aaad26df40953651196d8d9a594f62eb2d083a5bf3214c5c60218b3a' 
  AND token = 'ZiaU8XfXMqOz/KIVzWDqpqoakOJ+/FFGNX05FrUiieE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}