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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ace50eb1b80b25c357f4900c97f816bafa90d10bff28ea70df8f9d05f5e3c1c' 
  AND token = 'AJSzy0swB/E4XLS6K6W/25qJ2dp5CXqXnRhZx8/sF+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}