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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac8bfa2b92c2c24395174282cd32e20a45bbf19eb66fa5242215c99936b37653' 
  AND token = 'FlJKFAACLcWVc2sGoV0sshDR2jNcAdxMlesNtShDRh0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}