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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6124e42ea1d7a6f0384867e40337cc33632e1bb463ea5f947858cd4f71c0cbdf' 
  AND token = '+DTHNFWqcXo5s+3iGEy4aUFsx/WQGQtbseRx0R3yAfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}