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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'feea4f600d01cabf0f7da2c9c002d3a32d3efc30fe49ff36fd53149150f08800' 
  AND token = '2dmQ/t2VJ5YeqLpIzjUrXZ7dGlAxlUs3pOiwlpoWqUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}