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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44e8bb2c5cfca1add2b1ce8e6d836336d4ad72503f3fe5e197e61e00c2096c9e' 
  AND token = 'qtTyhgIndmRCioI08/qdRc4gk/Rxp+0LhMzZ5lrkXRk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}